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421 Service Temporarily Unavailable

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I need a solution

Hi,

A client using my server for emails is having issues sending emails to a client using your service. The errors are:

Connection timed out H=cluster1.eu.messagelabs.com [195.245.230.83]

SMTP error from remote mail server after RCPT TO:<stook@tektura.com>: 421 Service Temporarily Unavailable

Can you see if our IP or their ISP IP has been temporarily blacklisted or why their emails are not getting through please??
server address is 91.146.110.198. 

the sender address is as follows:
246.12-30-62.static.virginmediabusiness.co.uk
Sender IP: 62.30.12.246

If it is temporary like your error sugests how long will it take to heal itself?
Thanks in advance for any help/advice it would be much appreciated.

Kind Regards

Mark

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